Doubts and Concerns about Isolated Maternal Hypothyroxinemia

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Doubts and Concerns about Isolated Maternal Hypothyroxinemia

There is evidence that isolated maternal hypothyroxinemia may have detrimental effects on both mother and foetus. Nonetheless, this condition is still far from being universally accepted as a separate thyroid disease, and a standard definition of this state of mild thyroid underfunction is still lacking. We will review the biochemical criteria used to define isolated maternal hypothyroxinemia, ...

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Isolated maternal hypothyroxinemia during pregnancy: Knowns and unknowns

Isolated maternal hypothyroxinemia (IMH) during pregnancy is defined as a low maternal T4 in the absence of TSH elevation. As IMH is common, with a prevalence of 1-2% in iodine-sufficient populations, and early research has suggested adverse effects on fetal neurodevelopment, it has been the focus of many studies in the last decade. In the current review, we first discuss the significance of IM...

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ژورنال

عنوان ژورنال: Journal of Thyroid Research

سال: 2011

ISSN: 2042-0072

DOI: 10.4061/2011/463029